北京科技大學化生學院生物工程與傳感技術(shù)研究中心研究生導師：杜鑫

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杜鑫

副教授/副研究員

辦公地點：--化生樓302

辦公電話：--

電子郵件：duxin@ustb.edu.cn

科研方向：具有階層（多級）結(jié)構(gòu)的納米材料的可控制備及其在納米藥物基因遞送載體、納米催化劑、多功能自清潔納米涂層、納米馬達等領域的應用研究

簡歷

2014/9~至今：北京科技大學，化學與生物工程學院，生物傳感中心，副教授/副研究員，碩導； 2012/07~2014/08：澳大利亞阿德萊德大學，化學工程學院，加入喬世璋教授課題組，博士后研究員；2007/09~2012/06：中國科學院理化技術(shù)研究所，物理化學專業(yè)，博士學位，導師：賀軍輝研究；2003/09~2007/06：南開大學，化學學院材料化學專業(yè)，理學學士學位。

科研業(yè)績

北京科技大學高水平拔尖人才引進計劃，啟動經(jīng)費30萬；國家自然科學基金-青年基金，29.82萬; 中央高校基礎科研業(yè)務費研究項目，10萬；中央高校基礎科研業(yè)務費研究項目，10萬；橫向經(jīng)費，25.6萬，中國科學院光化學轉(zhuǎn)換與功能材料重點實驗室開放課題，2萬元；北京科技大學基本科研業(yè)務費-化生學院特色理科建設項目，2萬元。

獲得獎勵/專利

1. 新南威爾士大學副校長博后獎學金；2.中科院三好學生標兵、所長獎學金、三星獎學金；3. 五項已經(jīng)授權(quán)的發(fā)明專利，三項在申請中。

招生計劃

每年招收2名碩士生，歡迎本科生來實習。

代表性論文論著

目前，在Adv. Mater., Adv. Funct. Mater., Biomaterials, Small等化學、材料和生物類重要期刊發(fā)表SCI研究論文80多篇，其中第一和通訊作者文章45篇，影響因子大于10的有5篇，引用超過2600次，高被引論文4篇，H指數(shù)為28，研究成果被國際網(wǎng)絡新聞ACS News Service Weekly PressPac, ChemistryView, MaterialViews等進行了廣泛關注報道。

代表性論文論著

1.X. Du*, F. Kleitz*, X. Li, H. Huang, X. Zhang, S. Z. Qiao*,Disulfide-bridged organosilica frameworks: Designed synthesis, redox-triggered biodegradation, and nanobiomedical applications" Adv. Funct. Mater.2018, 28, 1707325.

2.X. Du*, C. Zhao, M. Zhou, T. Y. Ma, H. Huang, M. Jaroniec, X. Zhang, S. Z. Qiao*, Hollow carbon nanospheres with tunable hierarchical pores for drug, gene and photothermal synergistic treatment. Small 2017, 13, 1602592.

3. X. Du*, C. Zhao, Y. Luan*, C. Zhang, M. Jaroniec, H. Huang, X. Zhang, S. Z. Qiao*, Dendritic porous yolk@ordered mesoporous shell structured heterogeneous nanocatalysts with enhanced stability. J. Mater. Chem. A2017, 5, 21560.

4. B. Shi,* X. Du*, J.Chen, L. Fu, M. Morsch, A. Lee, Y. Liu, N. Cole, R. Chung, Multifunctional hybrid nanoparticles for traceable drug delivery and intracellular microenvironment controlled multistage drug release in neurons. Small 2017, 13, 1603966

5. M. Zhou, X. Du*, W. Li, X. Li, H. Huang, Q. Liao, B. Shi, X. Zhang, M. Zhang*, One-pot synthesis of redox-triggered biodegradable hybrid nanocapsules with a disulfide-bridged silsesquioxane framework for promising drug delivery. J. Mater. Chem. B 2017, 5, 4455

6. X. Du, X. Li, L. Xiong, X. Zhang*, F. Kleitz, S. Z. Qiao*,Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery.

Biomaterials 2016, 91, 90.

7. X. Du*, X. Li, H. Huang, J. He, X. Zhang, Dendrimer-like hybrid particles with tunable hierarchical pores. Nanoscale 2015, 6173.

8. X. Du, S. Z. Qiao*, Dendritic silica particles with center-radial pore channels: promising platforms for catalysis and biomedicine applications. Small 2015, 11, 392.

9. X. Du, B. Y. Shi, J. Liang, J. Bi. S. Dai, S. Z. Qiao*, Developing functionalized dendrimer-like silica nanoparticles with hierarchical pores as advanced delivery nanocarriers. Adv. Mater. 2013, 25, 5981.

10. X. Du, L. Xiong, Y. Tang, S. Dai, F. Kleitz, S. Z. Qiao*, Intracellular microenvironment-responsive dendrimer-like mesoporous nanohybrids for responsive, traceable, effective and safe intracellular gene delivery. Adv. Funct. Mater. 2014, 24, 7627.

11. X. Du, B. Shi, Y. Tang, S. Dai, S. Z. Qiao*, Label-free dendrimer-like silica nanohybrids for traceable and controlled gene delivery. Biomaterials 2014, 35, 5580.

12. X. Du, B. Y. Shi, L. Xiong, S. Dai, S. Z. Qiao*, ɣ-PGA coated mesoporous ailica nanoparticles with covalently attached prodrug for enhanced cellular uptake and intracellular GSH-responsive release. Adv. Healthcare. Mater. 2015, 4, 771.

13. X. Du, L. Yao, J. He*,One-pot fabrication of noble-metal nanoparticles that are encapsulated in hollow silica nanospheres: dual roles of poly (acrylic acid), Chem. Eur. J. 2012, 18, 7878.

14. X. Du, J. He*, Amino-functionalized silica nanoparticles with center-radially hierarchical mesopores as ideal catalyst carriers. Nanoscale2012, 4, 852.

15. X. Du, J. He*, Facile fabrication of hollow mesoporous silica nanospheres for superhydrophilic and visible/ Near-IR antireflection coatings. Chem. Eur. J. 2011, 17, 8165.

16. X. Du, J. He, A self-templated etching route to surface-rough silica nanoparticles for superhydrophobic coatings. ACS Appl. Mater. Interface 2011, 3, 1269.

研究生培養(yǎng)情況

趙彩霞（優(yōu)秀畢業(yè)生和畢業(yè)論文），李瑋克（優(yōu)秀畢業(yè)生,1等獎學金），周夢蕓（1等獎學金），王雨露（國家獎學金），軒曉膩，邢義（已畢業(yè)學生均有高水平論文發(fā)表）