西南大學生命科學學院研究生導師：馬鳴

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西南大學生命科學學院研究生導師馬鳴介紹如下：

馬鳴, 教授, 博士生導師。2007年獲新加坡國立大學博士學位。2008-2009年在耶魯大學醫(yī)學院腎內(nèi)科從事博士后研究工作，2010-2017年被聘為副研究科學家。2017年入職西南大學生命科學學院。

馬鳴實驗室的主攻方向是“腎臟發(fā)育與腎臟遺傳病研究”。其研究成果在以第一作者發(fā)表在Nature Genetics (Article), Cold Spring Harbor Perspectives in Biology, PLoS Genetics等雜志上。2013年美洲華人腎臟協(xié)會就其在腎臟病研究領(lǐng)域的貢獻授予了獎狀(Chinese American Society of Nephrology Outstanding Trainee Award)。2014年獲得美國多囊腎病基金會的科研基金(PKD Foundation) Research Grant-In-Aid。2017年入選第13批“青年千人”。現(xiàn)主持國家自然科學基金面上項目。

實驗室以小鼠，大鼠和斑馬魚為模型，研究方向為：

1.囊腫病的發(fā)病機理

2.纖毛在器官發(fā)育和穩(wěn)態(tài)維持中的功能

3.腎臟上皮細胞分化

代表論文:

Valeria Padovano, Ivana Y. Kuo, Lindsey K. Stavola, Hans R. Aerni, Benjamin J. Flaherty, Hannah C. Chapin, Ming Ma, Stefan Somlo, Alessandra Boletta, Barbara E. Ehrlich, Jesse Rinehart, and Michael J. Caplan. (2017). The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function. Molecular Biology of the Cell. 28(2):261-269.
 
Ming Ma, Anna-Rachel Gallagher, Stefan Somlo. (2017). Ciliary mechanisms of cyst formation in polycystic kidney disease. Cold Spring Harbor Perspectives in Biology. 9(11). pii: a028209. doi: 10.1101/cshperspect.a028209.(封面)(pdf1)
 
Yuanyuan Li, Xin Tian, Ming Ma, Shanshan Kong, Stefan Somlo, Zhaoxia Sun (2016). Deletion of the Joubert syndrome gene Arl13b leads to cystic kidney in mouse. Journal of the American Society of Nephrology. 27(12): 3628-3638.
 
4.Ming Ma, Xin Tian, Peter Igarashi, Gregory J. Pazour, and Stefan Somlo (2013). Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease. Nature Genetics. (Article) 45 (9) 1004-1012. (pdf2)

Ellen F. Carney “Polycystic kidney disease: Cyst growth and cilia in ADPKD” in Nature Review Nephrology. 9, 555 (2013). 突出推薦
Ong A and Streets A: F1000 Prime Recommendation of [Ma M et al., Nat Genet 2013]. In F1000Prime, 30 Sep 2013. 推薦
Patankar JV. Novel cilia-dependent pathway activates rapid cyst growth in autosomal dominant polycystic kidney disease. Clinical Genet. 2014 Mar; 85 (3):230-2. 熱點推薦
5.Hong Ma, Akashi Togawa, Keita Soda, Junhui Zhang, Sik Lee, Ming Ma, Zhiheng Yu, Thomas Ardito, Jan Czyzyk, Lonnette Diggs, Dominique Joly, Shinji Hatakeyama, Eiji Kawahara, Lawrence Holzman, Jun Lin Guan and Shuta Ishibe (2010). Inhibition of podocyte FAK protects against proteinuria and foot process effacement. Journal of the American Society of Nephrology. 21 (7) 1145-1156.

6.Chung-Der Hsiao, May-Su You, Ying-Jey Guh, Ming Ma, Yun-Jin Jiang, Pung-Pung Hwang (2007). A positive regulatory loop between foxi3a and foxi3b is essential for specification and differentiation of zebrafish epidermal ionocytes. PLoS ONE 2:e302.

7.Ming Ma and Yun-Jin Jiang (2007). Jagged2a-Notch signaling mediates cell fate choice in zebrafish pronephric duct. PLoS Genetics. 3(1) e18. (pdf3)

8.Ming Ma, Teck Koon Tan and Sek Man Wong (2003). Identification and molecular phylogeny of Epulorhiza isolates from tropical orchids. Mycological Research. 107: 1041-1049.

實驗室招收對生物醫(yī)學領(lǐng)域感興趣的博士后，博士研究生，碩士研究生和本科生。歡迎電郵聯(lián)系，電子郵箱skymaming@swu.edu.cn