蘭州大學(xué)

姓   名：白德成
Name： Bai Decheng
職 務(wù)：教授
Duty：  Professor
E-mail：bdc@lzu.edu.cn

一、 科研方向

1、腦細(xì)胞損傷與血粘度增高的相關(guān)性研究
2、腦外傷與血腦屏障開(kāi)放的實(shí)驗(yàn)研究
在研項(xiàng)目
1、腦紅蛋白對(duì)慢性進(jìn)行性腦缺血缺氧的保護(hù)作用研究 甘肅省自然科學(xué)基金 2.0萬(wàn)
2、慢性進(jìn)行性腦缺血缺氧與腦紅蛋白表達(dá)的相關(guān)性研究 蘭州大學(xué)醫(yī)學(xué)基金 0.7萬(wàn)
3、阿司匹林腦保護(hù)作用的實(shí)驗(yàn)研究 甘肅省新藥臨床前研究重點(diǎn)實(shí)驗(yàn)室創(chuàng)新基金 2.0萬(wàn)元
ResearchInterests：
1、The correlation study of injury of brain cells and high blood viscosity.
2.、The experimental study of brain trauma and blood brain barrier opening.
Reserching project：
1. Protective effect of neuroglobin on chronic anoxia- Ischemic change of the brain
2、The correlation between expression of neuroglobin and anoxia- Ischemic change of the brain
3、The experimental research of brain protection of Aspirin
 
二、榮譽(yù)稱號(hào)及獎(jiǎng)勵(lì)

榮譽(yù)稱號(hào)：甘肅省高等學(xué)校跨世紀(jì)學(xué)科帶頭人
獎(jiǎng)      勵(lì)：
1、 貓皮質(zhì)-后索核-脊髓通路的實(shí)驗(yàn)形態(tài)學(xué)研究 甘肅省衛(wèi)生廳科技成果獎(jiǎng) 二等1985.07
2、胚胎脊髓組織移植修復(fù)脊髓損傷實(shí)驗(yàn)研究 甘肅省衛(wèi)生廳科技進(jìn)步獎(jiǎng) 三等  1993.06
3、手部神經(jīng)損傷修復(fù)的實(shí)驗(yàn)與臨床研究 甘肅省科委科技進(jìn)步獎(jiǎng) 三等  1996.04.
4、外科手術(shù)學(xué)實(shí)驗(yàn)教學(xué)方法探索 甘肅省政府教學(xué)成果獎(jiǎng) 二等1997.05  
5、大鼠嗅結(jié)節(jié)與腦干某些核團(tuán)間的聯(lián)系 甘肅省衛(wèi)生廳科技進(jìn)步獎(jiǎng) 三等  1997.08
6、教學(xué)、科研、生產(chǎn)為一體的實(shí)驗(yàn)動(dòng)物學(xué)教學(xué)探索 甘肅省政府教學(xué)成果獎(jiǎng) 二等1999.12
7、 皮質(zhì)-腦干核-脊髓系統(tǒng)和皮質(zhì)-腦干核-小腦系統(tǒng)的形態(tài)學(xué)研究 甘肅省教育廳科技進(jìn)步獎(jiǎng) 二等2000.12
8、皮質(zhì)-腦干-脊髓系統(tǒng)的形態(tài)學(xué)研究 甘肅省科技進(jìn)步獎(jiǎng) 二等2001.4
9、葡萄籽中原花青素對(duì)阿霉素增效減毒作用及機(jī)理研究 甘肅省科技進(jìn)步獎(jiǎng) 二等 2007.05
honors and awards：
honors:cross-century academic leader in Colleges and Universities of Gansu Province
awards:
1、An experimental study on the organization of cortico dorsofuniculo-spinal pathway in the cat. The second prize of Scientific Research Achievements by Health Department of Gansu Province,1985.07
2、Renovation of rat spinal cord injury by transplantation of rat embryo spinal cord tissue .The third prize of scientific and technological advance Achievements by Health Department of Gansu Province,1993.06
3、The experimental and clinical research therapeutic effect on neural injury in the hand.The third prize of scientific and technological advance Achievements by Science Committee of Gansu Province,1996.04
4、The research of the course of operative surgery and the way of experimental teaching.The second prize of teaching research in Gansu Province,1997.05
5、Connections between the olfactory tubercle and some of brainstem nuclei in rat.The third prize of scientific and technological advance Achievements by Health Department of Gansu Province,1997.08
6、The teaching exploration of scientific research, teaching and production combining in  laboratory animal science.The second prize of teaching research in Gansu Province,1999.12
7、Morphological study of cortical-brainstem nuclei-spinal system and cortical-brainstem nuclei- cerebellum system. The second prize of scientific and technological advance Achievements by Education Department of Gansu Province,1997.08
8、Morphological study of cortical-brainstem-spinal system.The second prize of scientific and technological advance Achievements by Gansu Province, 2001.04
9、Synergy and attenuation of doxorubicin activities by proanthocyanidins from grape seeds The second prize of scientific and technological advance Achievements by Gansu Province, 2007.05

三、個(gè)人簡(jiǎn)歷

1974年?1977年   原蘭州醫(yī)學(xué)院醫(yī)療系醫(yī)療專業(yè)。
1981年?1984年   原蘭州醫(yī)學(xué)院神經(jīng)解剖學(xué)專業(yè)  碩士研究生。
1977年?1989年   原蘭州醫(yī)學(xué)院解剖教研室任助教、講師。
1990年?2004年   原蘭州醫(yī)學(xué)院外科手術(shù)學(xué)教研室任講師、副教授，設(shè)備處副處長(zhǎng)、國(guó)資處處長(zhǎng)，教學(xué)科研儀器報(bào)損報(bào)廢鑒定專家組成員。
2005年?2007年   蘭州大學(xué)臨床醫(yī)學(xué)院外科手術(shù)學(xué)教研室任教授，實(shí)驗(yàn)室與設(shè)備管理處處長(zhǎng)，教學(xué)科研儀器報(bào)損報(bào)廢鑒定專家組成員。
2007年?至    今   蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院外科手術(shù)學(xué)教研室任教授，實(shí)驗(yàn)室與設(shè)備管理處處長(zhǎng)，教學(xué)科研儀器報(bào)損報(bào)廢鑒定專家組成員。
Resume（including education background， English）：
1974至1977   Medical departments medical majors, Lanzhou Medical College。
1978至1984   Neuroanatomical majors,Lanzhou Medical College  Postgraduate。
1977至1989   Department of Anatomy, Lanzhou Medical College  Assistant and Instructor。
1990至2004   Department of Operative Surgery, Lanzhou Medical College  Instructor and Associate Professor, Deputy Director of the Equipment Department, Division Chief of State-owned Property Administration, Member of Identification Specialists in reported as loss and discard of Teaching and Scientific Instruments and Facilities。
2005至2007   Department of Operative Surgery of Clinical Medical College Lanzhou University     Professor, Division Chief of Laboratory and  Equipment Management Department, Member of Identification Specialists in reported as loss and discard of Teaching and Scientific Instruments and Facilities。
2007 until now   Department of Operative Surgery of Basic Medical College Lanzhou University  Professor, Division Chief of Laboratory and  Equipment Management Department, Member of Identification Specialists in reported as loss and discard of Teaching and Scientific Instruments and Facilities。

四、發(fā)表論文

1984   大腦皮質(zhì)向三叉神經(jīng)脊束尾側(cè)亞核的投射
1985   大腦皮質(zhì)向后索核投射的試驗(yàn)形態(tài)學(xué)研究
1985   皮質(zhì)-后索核-脊髓通路的形態(tài)學(xué)研究
1985   皮質(zhì)-后索核-脊髓通路的研究現(xiàn)狀和簡(jiǎn)史
1986   中縫核族向嗅前核的投射
1987   臂旁核向大腦皮質(zhì)的投射
1987   臂旁核-嗅球傳入纖維的又一來(lái)源
1988   貓Darkschewisch`s核向大腦皮質(zhì)的投射
1988   腦干神經(jīng)元向小腦絨球和脊髓的分支投射
1988   The projections of the cerebellar nuclei to the cerebellar cortex and the spinal cord
1990   大鼠視神經(jīng)傳出纖維的HRP法結(jié)合熒光追逐法研究
1992   皮質(zhì)-巨細(xì)胞網(wǎng)狀核-脊髓通路--HRP結(jié)合潰變電鏡法研究
1992   局解手術(shù)學(xué)協(xié)作教學(xué)的可行性和必要性
1993   單側(cè)胸鎖乳突肌缺如一例的巨微觀察
1994   局解、手術(shù)學(xué)協(xié)作教學(xué)初探
1995   恒河猴皮質(zhì)脊髓束與脊髓神經(jīng)元的突觸聯(lián)系
1995   大鼠大腦皮質(zhì)-下橄欖-小腦通路中的突觸復(fù)合體
1995   大鼠后根-楔外側(cè)核-小腦傳入通路的HRP潰變電鏡法研究
1996   SD大鼠皮質(zhì)小腦前核纖維終扣的電鏡觀察
1996   蘭州醫(yī)學(xué)院SPF小鼠飼育設(shè)施的設(shè)計(jì)與建設(shè)
1997   大鼠大腦皮質(zhì)投向小腦前核纖維的超微結(jié)構(gòu)和突觸聯(lián)系
1997   小鼠25s神經(jīng)生長(zhǎng)因子對(duì)大鼠、小鼠受損坐骨神經(jīng)再生的影響
1997   局解、手術(shù)學(xué)協(xié)作教學(xué)效果分析
1997   皮質(zhì)-PMRN-小腦通路--HRP結(jié)合潰變電鏡法研究
1997   大鼠PMRN中皮質(zhì)纖維終末的超微結(jié)構(gòu)觀察
1997   大鼠大腦皮質(zhì)-外側(cè)網(wǎng)狀核-小腦通路
1998   皮質(zhì)-網(wǎng)狀-脊髓通路─HRP法結(jié)合潰變電鏡法研究
1998   皮質(zhì)腦干纖維終末的超微結(jié)構(gòu) 潰變電鏡法研究
1999   大腦皮質(zhì)-小腦前核-小腦通路-- HRP結(jié)合潰變電鏡法研究
1999   大白鼠小腦前核中皮質(zhì)纖維與小腦投射神經(jīng)元間的突觸聯(lián)系
2003   實(shí)驗(yàn)性高粘血癥對(duì)腦組織丙二醛和超氧化物歧化酶含量的影響
2003   Arsenic trioxide inhibits P-glycoprotein expression of multidrug-resistant human leukemia ells that overexpress mdr-1 gene and induces apoptosis
2003   Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide
2004   高血粘度對(duì)小鼠腦細(xì)胞內(nèi)游離鈣濃度及腦組織丙二醛含量的影響
2004   小鼠腦細(xì)胞內(nèi)游離鈣濃度與高血粘度致腦血管病的相關(guān)性
2005   高血粘度大鼠血液有形成分及血液流變性的動(dòng)態(tài)觀察
2005   Proanthocyanidi from grape seeds enhances doxorubicin- induced antitumor effect and rveres drug resistance in doxorubicin-resistant K562/DOX cells
2005   Proanthocyanidin from grape seeds enhances anti-tumor effect of doxorubicin both in vitro and in vivo
2008   外源性鋅對(duì)缺氧神經(jīng)元的保護(hù)作用
2008   化學(xué)性缺氧致大鼠腦細(xì)胞[Ca2+]i和腦紅蛋白表達(dá)變化及阿司匹林干預(yù)研究

五、學(xué)術(shù)團(tuán)隊(duì)

趙秉江（教師）   程   菊（教師）  趙麗霞（學(xué)生）