北京科技大學

溫永強

教授 化學與生物工程學院副院長

辦公地點：化生樓505

辦公電話：82375840

電子郵件：wyq_wen@ustb.edu.cn

科研方向：智能響應性分子與材料 DNA納米技術 納米生物醫用與綠色健康材料

簡歷

2005年畢業于中科院化學研究所，獲博士學位； 2005.7-2011.06中科院化學所，助理研究員，副研究員； 2008.8-2009.8 加拿大McGill 大學，博士后，加拿大先進研究學會青年研究員 2011.07 北京科技大學，教授。

科研業績

主持及參與國家及省部級研究項目10余項。近五年，作為項目負責人主持了國家自然科學基金、北京市自然科學基金、教育部新世紀人才支持計劃等多項研究項目；作為科研骨干參加了多項863，973、國家重點研發計劃項目。申請專利20項，已獲得授權11項。

獲得獎勵/專利

曾獲中科院院長獎優秀獎； 中科院優秀博士學位論文； 全國優秀博士學位論文提名論文； 加拿大CIFAR (Canadian Institute for Advanced Research) 青年研究員并獲得資助； 教育部新世紀人才。

招生計劃

每年招收碩士研究生2-3名，博士生1-2名

代表性論文論著

[1]. Yansheng Li, Yanli Ma, Xiangyu Jiao, Tingyu Li, Zhehao Lv, Chaoyong James Yang*, Xueji Zhang*, Yongqiang Wen*. “Control of Capillary Behavior Through Target-Responsive Hydrogel Permeability Alteration for Sensitive Visual Quantitative Detection”, Nat. Commun. 2019, 10, 1036.

[2]. Kexin Zhang, Xiufeng Bai, Zhipeng Yuan, Xintao Cao, Xiangyu Jiao, Yansheng Li, Yan Qin*, Yongqiang Wen*, Xueji Zhang, Layered Nanofiber Sponge with an Improved Capacity for Promoting Blood Coagulation and Wound Healing, Biomaterials 2019, DOI: 10.1016/j.biomaterials.2019.03.008

[3]. Yao Huang, Zhipeng Yuan, Dan Zhao, Fang Wang, Kexin Zhang, Yansheng Li, Yongqiang Wen*, Changtao Wang. “Polymyxin B Immobilized Nanofiber Sponge for Endotoxin Adsorption”, Eur. Polym. J. 2019, 110, 69-75.

[4]. Zhu Zhu, Yibo Zhang, Yanli Shang,* Yongqiang Wen*. Electrospun Nanofibers Containing TiO2 for The Photocatalytic Degradation of Ethylene and Delaying Postharvest Ripening of Bananas[J]. Food Bioprocess Technol, 2019,12:281-287

[5]. Yibo Zhang, Ye Zhang, Zhu Zhu, Xiangyu Jiao, Yanli Shang,* Yongqiang Wen*. Encapsulation of Thymol in Biodegradable Nanofiber via Coaxial Eletrospinning and Applications in Fruit Preservation[J]. J. Agric. Food Chem.2019, 67, 1736–1741

[6]. Fang Wang, Lingyun Zhang, Xiufeng Bai, Xintao Cao, Xiangyu Jiao, Yan Huang, Yansheng Li, Yan Qin*, Yongqiang Wen*. “Stimuli-Responsive Nanocarrier for Co-delivery of MiR-31 and Doxorubicin to Suppress High MtEF4 Cancer”, ACS Appl. Mater. Inter. 2018, 10, 22767-22775.

[7]. Yansheng Li, Xiangyu Jiao, Xin Du, Fang Wang, Qianhui Wei, Yongqiang Wen*, Xueji Zhang*. “Wettability Alteration in Functional Capillary Tube for Visual Quantitative Point of Care Testing”, Analyst 2018, 143, 3001 – 3005.

[8]. Zhipeng Yuan, Yansheng Li, Dan Zhao, Kexin Zhang, Fang Wang, Changtao Wang, Yongqiang Wen*. “High Efficiency 3D Nanofiber Sponge for Bilirubin Removal used in Hemoperfusion”, Colloid. Surface. B 2018, 172, 161-169.

[9]. Yaya Cheng, Xiangyu Jiao, Liang Zhao, Yang Liu, Fang Wang, Yongqiang Wen*, Xueji Zhang. “Wetting transition in Nanochannels for Biomimetic Capless-blocking On-Demand Drug Transport”, J. Mater. Chem. B 2018, 6, 6269-6277.

[10]. Fang Wang, Zemin Wang, Yansheng Li, Liang Zhao, Yongqiang Wen*, Xueji Zhang. “Cap-free Dual Stimuli-Responsive Biodegradable Nanocarrier for Controlled Drug Release and Chemo-Photothermal Therapy”, J. Mater. Chem. B 2018, 6, 8188- 8195.

[11]. Ming Li, Zhipeng Yuan, Fei Yu, Feng Rao, Weng Jian, Baoguo Jiang, Yongqiang Wen*, Peixun Zhang*. “Microfluidic-based Screening of Resveratrol and Drug-loading PLA/Gelatine Nano-scaffold for the Repair of Cartilage Defect”. Artif. Cell. Nanomed. B 2018, 46, 336-346

[12]. Fei Yu, Ming Li, Zhipeng Yuan, Feng Rao, Xingxing Fang, Baoguo Jiang, Yongqiang Wen*, Peixun Zhang*. “Mechanism Research on a Bioactive Resveratrol-PLA-Gelatin Porous Nano-scaffold in Promoting the Repair of Cartilage Defect”, Int. J. Nanomed. 2018, 13, 7845–7858.

[13]. Yaya Cheng, Xiangyu Jiao, Tailin Xu, Wenqian Wang, Yu Cao, Yongqiang Wen*, Xueji Zhang. Free-blockage Mesoporous Anticancer Nanoparticles Based on ROS-responsive Wetting Behavior of Nanopores, Small 2017, 13, 1701942.

[14] . Wenqian Wang, Yaya Cheng, Yansheng Li, Hao Zhou, Liping Xu, Yongqiang Wen*, Liang Zhao, Xueji Zhang*. Enrichment and Viability Inhibition of Circulating Tumor Cells on a Dual Acid‐Responsive Composite Nanofiber Film. ChemMedChem, 2017, 12, 529-536.

[15] . Xiangyu Jiao, Yanan Li, Fengyu Li, Ruijuan Sun, Wenqian Wang, Yongqiang Wen*, Yanlin Song, Xueji Zhang*. Voltage-Responsive Controlled Release Film with Cargo Release Self-Monitoring Property Based on Hydrophobicity Switching. ACS Applied Materials & Interfaces, 2017, 9, 10992-10999.

[16] .Xiangyu Jiao, Ruijuan Sun, Yaya Cheng, Fengyu Li, Xin Du, Yongqiang Wen*, Yanlin Song, Xueji Zhang*. A Voltage‐Responsive Free‐Blockage Controlled‐Release System Based on Hydrophobicity Switching. Chemphyschem, 2017, 18, 1317-1324.

[17]. Xiangyu Jiao, Yanan Li, Fengyu Li, Wenqian Wang, Yongqiang Wen*, Yanlin Song, Xueji Zhang*. pH-Responsivenano sensing valve with self-monitoring state property based on hydrophobicity switching. Rsc Advances, 2016, 6, 52292-52299.

[18]. Yansheng Li, Hongwu Du, Wenqian Wang, Peixun Zhang, Liping Xu,Yongqiang Wen*, Xueji Zhang. A Versatile Multiple Target Detection System Based on DNA Nano-assembled Linear FRET s. Scientific Reports, 2016, 6, 26879.

[19]. Yan Huang, Wenqian Wang, Tingting Wu, Liping Xu, Yongqiang Wen*, Xueji Zhang*. A three-line lateral flow biosensor for logic detection of microRNA based on Y-shaped junction DNA and target recycling amplification. Analytical and Bioanalytical Chemistry, 2016, 408, 8195-8202.

[20]. Wanyuan Gui, Wenqian Wang, Xiangyu Jiao, Lifeng Chen, Yongqiang Wen*, Xueji Zhang, Dual-cargo Selectively Controlled Release Based on pH-Responsive Mesoporous Silica System, ChemPhysChem 2015, 16, 607-613.

[21] .Wenqian Wang, Linfeng Chen, Li-ping Xu, Hongwu Du, Yongqiang Wen,* Yanlin Song, Xueji Zhang*, A Free-blockage Controlled Release System Based on the Hydrophobic/Hydrophilic Conversion of Mesoporous Silica Nanopores, Chemistry - A European Journal 2015, 21, 2680-2685.

[22]. Linfeng Chen, Wenqian Wang, Bin Su, Yongqiang Wen*, Chuanbao Li, Mingzhu Li, Xiaodi Shi, Hongwu Du, Yanlin Song*, Lei Jiang. A Light-Responsive Release Platform by Controlling the Wetting Behavior of Hydrophobic Surface. ACS Nano 2014, 8 , 744–751.

[23]. Wenqian Wang, Yongqiang Wen*, Liping Xu, Hongwu Du, Yabin Zhou, Zhang Xueji*, A Selective Release System Based on Dual-drug Loaded Mesoporous Silica for Nanoparticle-assisted Combination Therapy, Chemistry - A European Journal 2014, 20, 7796-7802.

研究生培養情況