北京理工大學

北京理工大學化學與化工學院研究生院導(dǎo)師杜大明介紹如下：

教師姓名：杜大明
出生年月：1967年11月
政治面貌：中共黨員
所在學科：應(yīng)用化學
職稱：教授，博士生導(dǎo)師
聯(lián)系電話：010-68914985/68918716
郵箱：dudm@bit.edu.cn
通訊地址：北京市海淀區(qū)中關(guān)村南大街5號
郵編：100081
 
教育經(jīng)歷

1992 年 9 月—1995 年 6 月，南開大學有機化學專業(yè)，獲得理學博士學位。
1989 年 9 月—1992 年 7 月，南開大學有機化學專業(yè)，獲得理學碩士學位。
1985 年 9 月—1992 年 7 月，鄭州大學化學專業(yè)，獲得理學學士學位。
 
工作經(jīng)歷

2008 年 9 月—目前，北京理工大學化工與環(huán)境學院
1999 年 4 月—2008 年 8 月，北京大學化學與分子工程學院
1995 年 7 月—1999 年 3 月，山東大學化學學院
（其間：香港中文大學和香港科技大學）
 
研究領(lǐng)域

不對稱催化合成；有機合成新方法和綠色化學合成；藥物及中間體合成
 
獲獎情況

1.教育部新世紀優(yōu)秀人才支持計劃獲得者
2.Thieme Journal Award 2009
3.Tetrahedron: Asymmetry Most Cited Paper 2004-2007 Award
4.第八屆北京青年優(yōu)秀科技論文評選二等獎
 
社會兼職
 
教學工作

2015 年教學工作
1.本科生《化學制藥工藝學》，32 學時；
2.本科生《學科進展報告》，2 學時；
3.  碩士研究生《高等有機化學》，54 學時
2014 年教學工作
1.本科生《化學制藥工藝學》，32 學時；
2.本科生《學科進展報告 A》，2 學時；
3.碩士研究生《高等有機化學》，54 學時
 
論文與著作

1.Jiahuan Peng, Bo-Liang Zhao, Da-Ming Du*. A combination of metal and
organocatalysis: Highly diastereo- and enantioselective construction of fluorinated
2-aminocyclopenta[b]pyran derivatives[J]. Advanced Synthesis & Catalysis, 2015,
357(16-17), 3639-3647.
2.Jun-Hua Li, Da-Ming Du*. Phosphine-catalyzed cascade reaction of unsaturated
pyrazolones with alkyne derivatives: Efficient synthesis of pyrano[2,3-c]pyrazoles
and spiro-cyclopentanone-pyrazolones[J]. Advanced Synthesis & Catalysis, 2015,
DOI: 10.1002/adsc.201500675.
3.Jun-Hua Li, Ting-Fan Feng, Da-Ming Du*. Construction of
spirocyclopropane-linked heterocycles containing both pyrazolones and oxindoles
through Michael/alkylation cascade reaction[J]. The Journal of Organic Chemistry,
2015, 80(22), 11369-11377..
4.Bo-Liang Zhao, Ye Lin, Hao-Hao Yan, and Da-Ming Du*. Squaramide-catalyzed
asymmetric cascade aza-Michael/Michael addition reaction for synthesis of chiral
trisubstituted pyrrolidines[J]. Organic & Biomolecular Chemistry, 2015, 13(46),
11351-11361.
5.Bo-Liang Zhao, Da-Ming Du*. Chiral squaramide-catalyzed Michael/alkylation
cascade reaction for the asymmetric synthesis of nitro-spirocyclopropanes[J].
European Journal of Organic Chemistry, 2015, (24), 5350-5359.
6.Bo-Liang Zhao, Da-Ming Du*. Organocatalytic enantioselective cascade
aza-Michael/Michael addition sequence for asymmetric synthesis of chiral
spiro[pyrrolidin-3,3'-oxindole]s[J]. Asian Journal of Organic Chemistry, 2015, 4(10),
1120-1126.3
7.Bo-Liang Zhao, Da-Ming Du*. Chiral-squaramide-catalyzed sulfa-Michael/aldol
cascade reactions for asymmetric synthesis of spirothiochromanones[J]. Asian
Journal of Organic Chemistry, 2015, 4(8), 778-787.
8.Jun-Hua Li, Da-Ming Du*, Enantioselective cascade double Michael addition of
3-nitro-2H-chromenes and acyclic enones: Efficient synthesis of functionalized
tricyclic chroman derivatives[J]. Organic & Biomolecular Chemistry, 2015, 13(37),
9600-9609.
9.Jun-Hua Li, Da-Ming Du*. Enantioselective synthesis of chiral heterocycles
containing both chroman and pyrazolone derivatives catalysed by a chiral
squaramide[J]. Organic & Biomolecular Chemistry, 2015, 13(20), 5636-5645.
10.Jun-Hua Li, Da-Ming Du*. Enantioselective synthesis of biologically active
dihydropyrano-[2,3-c]pyrazoles catalysed by a chiral squaramide[J]. Chinese
Journal of Chemistry, 2015, 33(4), 418–424.
11.Jun-Hua Li, Da-Ming Du*. Organocatalyzed enantioselective cascade
aza-Michael/Michael addition for the construction of highly functionalized
spiropyrazolone tetrahydroquinolines[J]. Chemistry-An Asian Journal, 2014, 9(11),
3278–3286.
12.Yu Gao, Da-Ming Du*. Asymmetric Michael addition/intramolecular cyclization
catalyzed by bifunctional tertiary amine-squaramides: construction of chiral
2-amino-4H-chromene-3-carbonitrile derivatives[J]. Chemistry-An Asian Journal,
2014, 9(10), 2970–2974.
13.Bo-Liang Zhao, Lei Liu, Da-Ming Du*. Chiral squaramide-catalyzed
sulfa-Michael/aldol cascade for the asymmetric synthesis of spirocyclic
tetrahydrothiophene chromanone derivatives[J]. European Journal of Organic
Chemistry, 2014, (35), 7850–7858.
14.Hai-Xiao He, Da-Ming Du*. Organocatalytic enantioselective Strecker reaction of
imines containing a thiazole moiety by using a cinchona-based squaramide
catalyst[J]. European Journal of Organic Chemistry, 2014, (28), 6190–6199.
15.Bo-Liang Zhao, Da-Ming Du*. Chiral squaramide-catalysed one-pot
enantioselective sulfa-Michael addition/thioesterification of thiols
with ,-unsaturated N-acylated succinimides[J]. Organic & Biomolecular Chemistry,
2014, 12(10), 1585–1594.
16.Bo-Lliang Zhao, Da-Ming Du*. Catalytic asymmetric conjugate addition of
various -mercaptoketones to ,-unsaturated N-acylated oxazolidin-2-ones with
bifunctional organocatalyst[J]. RSC Advances, 2014, 4(52), 27346–27353.
17.Jun-Hua Li, Da-Ming Du*. Enantioselective synthesis of pyrazolone derivatives
catalysed by a chiral squaramide catalyst[J]. RSC Advances, 2014, 4(28), 14538–
14545.
18.Jiahuan Peng, Da-Ming Du*. Efficient enantioselective fluorination of -keto
esters/amides catalysed by diphenylamine-linked bis(thiazoline)-Cu(OTf)2
complexes[J]. RSC Advances, 2014, 4(4), 2061–2067.
19.Ying-He Li, Bo-Liang Zhao, Yu Gao, Da-Ming Du*. Asymmetric synthesis of
3-substituted indole derivatives containing tetrahydrothiophene via cascade
Michael/Michael additions catalyzed by a chiral squaramide catalyst[J].
Tetrahedron:Asymmetry, 2014, 25(23), 1513–1519.
20.Sheng-Jian Jia, Da-Ming Du*. Enantioselective Friedel-Crafts alkylation of
indoles with  β,γ-unsaturated α-ketoesters catalyzed  by new squaramide-linked
bisoxazoline-Zn(OTf)2 complexes[J]. Tetrahedron:Asymmetry, 2014, 25(13-14), 980
–988.
21.Hai-Xiao He, Da-Ming Du*. Highly enantionselective Mannich reaction of imines
with tert-butyl acetoacetate catalysed by squaramide[J]. Tetrahedron: Asymmetry
2014, 25(8), 637–643.
22.Bo-Liang Zhao, Da-Ming Du*. Enantioselective synthesis of enol lactones from
tandem Michael addition/lactonization catalyzed by chiral squaramide catalyst[J].
Tetrahedron: Asymmetry, 2014, 25(4), 310–317.
23.Yi Yang, Daming Du*. Enantioselective construction of functionalized
thiochromans via squaramide-catalyzed asymmetric cascade
sulfa-Michael/Michael addition[J]. Chinese Journal of Chemistry 2014, 32(9), 853–
858.
24.Sheng-Jian Jia, Da-Ming Du*. Enantioselective chlorination of -keto esters and
amides catalyzed by chiral copper(II) complexes of squaramide-linked bisoxazoline
ligand[J]. Chinese Chemical Letters, 2014, 25(11), 1479–1484.
25.Wen Yang, Da-Ming Du*. Cinchona-based squaramide-catalysed cascade
aza-Michael-Michael addition: enantioselective construction of functionalized
spirooxindole tetrahydroquinolines[J]. Chemical Communications, 2013, 49(78),
8842–8844.
26.Wen Yang, Yi Yang, Da-Ming Du*. Squaramide-tertiary amine catalyzed
asymmetric cascade sulfa-Michael/Michael addition via dynamic kinetic resolution:
access to highly functionalized chromans with three contiguous stereocenters[J].
Organic Letters, 2013, 15(6), 1190–1193.
27.Wen Yang, Hai-Xiao He, Yu Gao, Da-Ming Du*. Organocatalytic enantioselective
cascade aza-Michael/Michael addition for the synthesis of highly functionalized
tetrahydroquinolines and tetrahydrochromanoquinolines[J]. Advanced Synthesis &
Catalysis, 2013, 355(18), 3670–3678.
28.Hai-Xiao He, Wen Yang, Da-Ming Du*. Enantioselective aza-Henry reaction of
imines bearing a benzothiazole moiety catalyzed by a cinchona-based
squaramide[J]. Advanced Synthesis & Catalysis, 2013, 355(6), 1137–1148.
29.Jun-Hua Li, Da-Ming Du*. Squaramide-catalysed enantioselective Michael
addition of pyrazolin-5-ones to nitroalkenes[J]. Organic & Biomolecular Chemistry,
2013, 11(36), 6215–6223.
30.Jianhuan Peng, Da-Ming Du*. Catalytic asymmetric tandem Friedel-Crafts
alkylation/ Michael addition reaction for the synthesis of highly functionalized
chromans[J]. Beilstein Journal of Organic Chemistry, 2013, 9, 1210–1216.
31.Hai-Xiao He, Da-Ming Du*. Squaramide-catalysed enantionselective Mannich
reaction of imines bearing a heterocycle with malonates[J]. RSC Advances, 2013,
3(37), 16349–16358.
32.Yang Jia, Da-Ming Du*. Catalyst-free, one-pot three-component 1,3-dipolar
cycloaddition of diethyl 2-aminomalonate, benzaldehydes and
3-nitro-2H-chromenes[J]. RSC Advances, 2013, 3(6), 1970–1975.
33.Yu Gao, Da-Ming Du*. Facile synthesis of chiral
2-amino-4-(indol-3-yl)-4H-chromene derivatives using thiourea as the catalyst[J].
Tetrahedron: Asymmetry, 2013, 24(20), 1312–1317.
34.Juan Dong, Da-Ming Du*. Highly enantioselective synthesis of Warfarin and its
analogs catalysed by primary amine-phosphinamide bifuncitonal catalysts[J].
Organic & Biomolecular Chemistry, 2012, 10(40), 8125–8131.
35.Wen Yang, Da-Ming Du*. Squaramide-catalysed enantio- and diastereoselective
sulfa-Michael addition of thioacetic acid to  α,β-disubstituted nitroalkenes[J].
Organic & Biomolecular Chemistry, 2012, 10(34), 6876–6884.
36.Yang Jia, Wen Yang, Da-Ming Du*. Asymmetric Friedel-Crafts alkylation of
indoles with 3-nitro-2H-chromenes catalyzed by diphenylamine-linked
bis(oxazoline) and bis(thiazoline) Zn(II) complexes[J]. Organic & Biomolecular
Chemistry, 2012, 10(24), 4739–4746.
37.Chunhua Luo, Yu Jin, Da-Ming Du*. Simple chiral sulfonamide primary amine
catalysed highly enantioselective Michael addition of malonates to enones[J].
Organic & Biomolecular Chemistry, 2012, 10(20), 4116–4123.
38.Wen Yang, Yang Jia, Da-Ming Du*. Chiral squaramide-catalyzed enantioselective
Michael addition of malonitrile to chacones[J]. Organic & Biomolecular Chemistry,
2012, 10(2), 332–338.
39.Jiahuan Peng, Da-Ming Du*. Asymmetric Friedel-Crafts alkylation of indoles with
nitrodienes and 2-propargyloxy-β-nitrostyrenes catalyzed by
diphenylamine-linked bis(oxazoline)-Zn(OTf)2 complexes[J]. European Journal of
Organic Chemistry, 2012, (21), 4042–4051.
40.Yu Jin, Da-Ming Du*. The synthesis of phosphine oxide-linked bis(oxazoline)
ligands and their application in asymmetric allylic alkylation[J]. Tetrahedron, 2012,
68(18), 3633–3640.
41.Wen Yang, Jingsi Wang, Da-Ming Du*. Chiral squaramide-catalyzed enantio-
and diastereoselective Michael addition of 3-substituted oxindoles to
nitroalkenes[J]. Tetrahedron: Asymmetry, 2012, 23(13), 972–980.
42.Yu Gao, Da-Ming Du*. Enantioselective synthesis of
2-amino-5,6,7,8-tetrahydro-5-oxo-4H-chromene-3-carbonitriles using squaramide
as the catalyst[J]. Tetrahedron: Asymmetry, 2012, 23(18-19), 1343–1349.
43.Yu Gao, Wen Yang, Da-Ming Du*. Efficient organocatalytic asymmetric synthesis
of 2-amino-4H-chromene-3-carbonitrile derivatives[J]. Tetrahedron: Asymmetry,
2012, 23(5), 339–344.
44.Shengjian Jia, Chunhua Luo, Daming Du*. Highly enantioselective Michael
addition of ketone to alkylidene malonates catalyzed by binaphthyl sulfonimides in
water[J]. Chinese Journal of Chemistry, 2012, 30(11), 2676–2680.
45.Wen Yang, Da-Ming Du*. Chiral squaramide-catalyzed highly diastereo- and
enantioselective direct Michael addition of nitroalkanes to nitroalkenes[J]. Chemical
Communications, 2011, 47(47), 12706–12708.
46.Wen Yang, Da-Ming Du*. Chiral squaramide-catalyzed highly enantioselective
Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes[J]. Advanced
Synthesis & Catalysis, 2011, 353(8), 1241–1246.
47.Wen Yang, Da-Ming Du*. Highly enantioselective Henry reaction catalyzed by
C2-symmetric modular BINOL-oxazoline Schiff base copper(II) complex generated
in situ[J]. European Journal of Organic Chemistry, 2011, (8), 1552–1556.
48.Xian Du, Han Liu, Da-Ming Du*. Synthesis and application of diphenyl sulfide
linked bis(imidazoline) ligands: Dramatic electronic effect of ligands on catalytic
behavior[J]. European Journal of Organic Chemistry, 2011, (4), 786–793.
49.Chunhua Luo, Da-Ming Du*. Highly enantioselective Michael addition of
ketones and an aldehyde to nitroalkenes catalyzed by a binaphthyl sulfonimide in
water[J]. Synthesis, 2011, (12), 1968–1973.
50.Wen Yang, Da-Ming Du*. Highly enantioselective Michael addition of
nitroalkanes to chalcones using chiral squaramides as hydrogen bonding
organocatalysts[J]. Organic Letters, 2010, 12(23), 5450–5453.
51.Han Liu, Da-Ming Du*. Development of diphenylamine-linked bis(imidazoline)
ligands and their application in asymmetric Friedel-Crafts alkylation of indole
derivatives with nitroalkenes[J]. Advanced Synthesis & Catalysis, 2010, 352(7), 1113
–1118.
52.Wen Yang, Han Liu, Da-Ming Du*. Efficient in situ three-component formation of
chiral oxazoline-Schiff base copper(II) complexes: towards combinatorial library of
chiral catalysts for asymmetric Henry reaction[J]. Organic & Biomolecular Chemistry,
2010, 8(13), 2956–2960.
53.Shurong Ban, Da-Ming Du*, Han Liu, Wen Yang. Synthesis of novel binaphthyl
sulfonimides and their application in the enantioselective Michael addition of
ketones to nitroalkenes[J]. European Journal of Organic Chemistry, 2010, (27), 5160
–5164.
54.Han Liu, Da-Ming Du*. Immobilization of diphenylamine-linked bis(oxazoline)
ligands and their application in asymmetric Friedel-Crafts alkylation of indole
derivatives with nitroalkenes[J]. European Journal of Organic Chemistry, 2010, (11),
2121–2131.
55.Xian Du, Han Liu, Da-Ming Du*. Rational tuning the rigidity of a ligand scaffold:
synthesis of diphenylsulfide-linked bis(oxazoline) ligands and their application in
asymmetric allylic alkylation[J]. Tetrahedron: Asymmetry, 2010, 21(2), 241–246.
56.Han Liu, Neng-Dong Wng, Da-Ming Du*. Direct experimental evidence for the
priority of flexible ligand skeleton in asymmetric Friedel-Crafts alkylation of indole
with nitroalkenes[J]. Letters in Organic Chemistry, 2010, 7(2), 114–120.
57.Han Liu, Da-Ming Du*. Recent advances in the synthesis of 2-imidazolines and
their applications in homogeneous catalysis[J]. Advanced Synthesis & Catalysis,
2009, 351(4), 489–519.
58.Wei Li, Han Liu, Da-Ming Du*. Mild michael addition of glycine imines to
aromatic nitroalkenes catalyzed by DBU with LiOTf as an additive[J]. Synlett, 2009,
(6), 925–928.
59.Jin Wang, Han Liu, Da-Ming Du*. Diphenylamine-derived bis-hydroxyamide
catalyzed asymmetric borane reduction of prochiral ketones[J]. Tetrahedron:
Asymmetry, 2009, 20(5), 605–609.
60.Qun-Sheng Guo, Da-Ming Du*. The practical synthesis of double axial chiral
guanidines[J]. Letters in Organic Chemistry, 2009, 6(3), 197–202.
61.Han Liu, Wei Li, DaMing Du*. Modification of diphenylamine-linked
bis(oxazoline) ligands: tuning of electronic effect and rigidity of ligand skeleton[J].
Science in China Series B: Chemistry, 2009, 52(9), 1321–1330.
62.Ning Chen, Min Zhu, Wei Zhang, Da-Ming Du, Jiaxi Xu*. Synthesis of
gem-disubstituted taurines by the regioselective ring-opening of 2,2-disubstituted
aziridines with sodium bisulfite and sulfite[J]. Amino acids, 2009, 37(2), 309-313.
63.Qun-Sheng Guo, Da-Ming Du*, Jiaxi Xu. The development of new double axially
chiral phosphoric acids and their catalytic asymmetric transfer hydrogenation of
quinolines[J]. Angewandte Chemie, International Edition, 2008, 47(4), 759–762.
64.Wen-Ming Zhou, Han Liu, Da-Ming Du*. Organocatalytic highly enantioselective
Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes[J]. Organic
Letters, 2008, 10(13), 2817–2820.
65.Han Liu, Shao-Feng Lu, Jiaxi Xu, Da-Ming Du*. Asymmetric Friedel-Crafts
alkylation of electron-rich N-heterocycles with nitroalkenes catalyzed by
diphenylamine-tethered bis(oxazoline) and bis(thiazoline)-Zn(II) complexes[J].
Chemistry-An Asian Journal, 2008, 3(7), 1111–1121.
66.Huihui?Li, Gu Yuan,* Daming Du. Investigation of formation, recognition,
stabilization, and conversion of dimeric G-quadruplexes of HIV-1 integrase
inhibitors by electrospray ionization mass spectrometry[J]. Journal of the American
Society of Mass Spectrometry, 2008, 19(4), 550–559.
67.Boyuan Wang, Wei Zhang, Leilei Zhang, Da-Ming Du, Gang Liu, Jiaxi Xu*.
Versatile synthesis of free and N-benzyloxycarbonyl protected 2,2-disubstituted
taurines[J]. European Journal of Organic Chemistry, 2008, (2), 350–355.
68.Juanjuan Du, Zhiyi Li, Da-Ming Du, Jiaxi Xu*. Unexpected influence and its origin
in rationally tuning the electronic effect of catalysts in the asymmetric borane
reduction of ketones[J]. Journal of Molecular Catalysis A: Chemistry, 2008, 284(1),
40–45.
69.Wei Zhang, Boyuan Wang, Ning Chen, Da-Ming Du, Jiaxi Xu*. Expeditious and
practical synthesis of various substituted taurines from amino alcohols[J]. Synthesis,
2008, (2), 197–200.
70.Min Zhu, Libo Hu, Ning Chen, Da-Ming Du, and Jiaxi Xu*. Synthesis of
NH-aziridines from vicinal amino alcohols via the Wenker reaction: scope and
limitation[J]. Letters in Organic Chemistry, 2008, 5(3), 212–217.
71.Juanjuan Du, Zhiyi Li, Da-Ming Du, Jiaxi Xu*. Improving enantioselectivity via
rationally tuning electronic effects of catalysts in the organocatalytic asymmetric
aldol reaction[J]. Arkivoc, 2008, Part (xvii), 145–156.
72.Han Liu, Jiaxi Xu, Da-Ming Du*. Asymmetric Friedel-Crafts alkylation of
methoxyfuran with nitroalkenes catalyzed by diphenylamine-tethered
bis(oxazoline)-Zn(II) complexes[J]. Organic Letters, 2007, 9(23), 4725–4728.
73.Libo Hu, Hui Zhu, Da-Ming Du, Jiaxi Xu*. Efficient synthesis of taurine and
structurally diverse substituted taurines from aziridines[J]. The Journal of Organic
Chemistry, 2007, 72(12), 4543–4546.
74.Bonan Li, Shuzong Cai, Da-Ming Du, Jiaxi Xu*. Synthesis of phosphinopeptides
via the Mannich ligation[J]. Organic Letters, 2007, 9(12), 2257–2260.
75.Bonan Li, Yikai Wang, Da-Ming Du, Jiaxi Xu*. Notable and obvious ketene
substituent-dependent effect of temperature on the stereoselectivity in the
Staudinger reaction[J]. The Journal of Organic Chemistry, 2007, 72(3), 990–997.
76.Libo Hu, Yikai Wang, Bonan Li, Da-Ming Du, Jiaxi Xu*. Diastereoselectivity in the
Staudinger reaction: a useful probe for investigation of nonthermal microwave
effects[J]. Tetrahedron, 2007, 63(38), 9387–9392.
77.Linge Ma, Peng Jiao, Qihan Zhang, Da-Ming Du, Jiaxi Xu*. Ligand and substrate
pi-stacking interaction controlled enantioselectivity in the catalytic asymmetric
aziridination[J]. Tetrahedron: Asymmetry, 2007, 18(7), 878–884.
78.Xiao Wang, Han Liu, Da-Ming Du, Jiaxi Xu*. Effect of the borane source on the
enantioselectivity in the chiral oxazaborolidine-catalyzed asymmetric borane
reduction of ketones[J]. Heteroatom Chemistry, 2007, 18(7), 740–746.
79.李伯男，梁勇，焦雷，胡立博，杜大明，許家喜*. 3-(噻吩-2-基)-β-內(nèi)酰胺的合成及其立
體化學[J].  化學學報, 2007, 65(16), 1643–1648.
80.Shao-Feng Lu, Da-Ming Du*, Jiaxi Xu, Shi-Wei Zhang. Asymmetric conjugate
addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric tridentate
bis(oxazoline) and bis(thiazoline) zinc complexes[J]. Journal of the American
Chemical Society, 2006, 128(23), 7418–7419.
81.Shao-Feng Lu, Da-Ming Du*, Jiaxi Xu. Enantioselective Friedel-Crafts alkylation
of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II)
complex[J]. Organic Letters, 2006, 8(10), 2115–2118.
82.Da-Ming Du*, Tao Fang, Jiaxi Xu, Shi-Wei Zhang. Structurally well-defined,
recoverable C3-symmetric tris(-hydroxy phosphoramide)-catalyzed
enantioselective borane reduction of ketones[J]. Organic Letters, 2006, 8(7), 1327–
1330.
83.Tao Fang, Jiaxi Xu, Da-Ming Du*. Highly enantioselective borane reduction of
prochiral ketones catalyzed by C3-symmetric tripodal -hydroxy amides[J]. Synlett,
2006, (10), 15591563.
84.Tao Fang, Jiaxi Xu, Da-Ming Du*. Facile synthesis of C3-symmetric tripodal
-hydroxy amide ligands and their Ti (IV) complex-catalyzed asymmetric addition of
diethylzinc to aldehydes[J]. Letters in Organic Chemistry, 2006, 3(10), 780–786.
85.Yikai Wang, Yong Liang, Lei Jiao, Da-Ming Du, Jiaxi Xu*. Do reaction conditions
affect the stereoselectivity in the Staudinger reaction?[J]. The Journal of Organic
Chemistry, 2006, 71(18), 69836990.
86.Linge Ma, Da-Ming Du, Jiaxi Xu. Asymmetric aziridination of 1,3-dienes
catalyzed by bisoxazoline-copper complexes[J]. Chirality, 2006, 18(8), 575–580.
87.Xiao Wang, Yikai Wang, Da-Ming Du, Jiaxi Xu*. Solvent-free, AlCl3-promoted
tandem Friedel-Crafts reaction of arenes and aldehydes[J]. Journal of Molecular
Catalysis A: Chemistry, 2006, 255(1-2), 31–35.
88.Jiaxing Huang, Da-Ming Du, Jiaxi Xu*. Facile synthesis of 1,1-disubstituted
taurines[J]. Synthesis, 2006, (2), 315–319.
89.Han Liu, Da-Ming Du, Jiaxi Xu*. Effect of the secondary reduction on the
enantioselectivity and function of additives in the oxazaborolidine-catalyzed
asymmetric borane reduction of ketones[J]. Helvetica Chimica Acta, 2006, 89(5),
1067–1074.
90.馬琳鴿,  杜大明, 許家喜.  在不對稱氮雜環(huán)丙烷化中雙噁唑啉配位空間大小對對映選擇
性的影響[J].  有機化學, 2006, 26(4), 568–572.
91.王一愷,  杜大明, 許家喜*.  微波對烯酮和亞胺形成-內(nèi)酰胺順反選擇性的影響[J].  遼寧石
油化工大學學報, 2006, 26(4), 94–95, 99.
92.Tao Fang, Da-Ming Du,* Shao-Feng Lu, Jiaxi Xu*. Synthesis of C3-Symmetric
tris(-hydroxy amide) ligands and their Ti(IV) complex-catalyzed enantioselective
alkynylation of aldehydes[J]. Organic Letters, 2005, 7(11), 2081–2084.
93.Da-Ming Du,* Shao-Feng Lu, Tao Fang, Jiaxi Xu*. Asymmetric Henry reaction
catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) complexes:
metal-controlled reversal of enantioselectivity[J]. The Journal of Organic Chemistry,
2005, 70(9), 3712–3715.
94.Linge Ma, Da-Ming Du, Jiaxi Xu*. Rational tuning chelate size of bis-oxazoline
ligands to improve enantioselectivity in the asymmetric aziridination of
chalcones[J]. The Journal of Organic Chemistry 2005, 70 (24), 10155–10158.
95.Jiaxing Huang, Fei Wang, Da-Ming Du, Jiaxi Xu*. An expeditious synthesis of
1-substituted and cyclic taurines[J]. Synthesis, 2005, (13), 2122–2128.
96.Zhan-Yue Wang, Da-Ming Du*, Jia-Xi Xu. Synthesis of novel chiral semicrown
ether-like bis(oxazoline) ligands and application in enantioselective
cyclopropanation of styrene[J]. Synthetic Communications, 2005, 35(2), 299–313.
97.Hui Chen, Da-Ming Du, Bin Fu, Meiyu He. Investigation on mass spectra
fragmentation mechanism of C2-symmetric chiral bis(oxazolines) and
bis(thiazolines)[J]. Chinese Journal of Chemistry, 2005, 23(6), 720–724.
98.Da-Ming Du, Paul R. Carlier*. Development of bivalent acetylcholinesterase
inhibitors as potential therapeutic drugs for alzheimer’s disease[J]. Current
Pharmaceutical Design, 2004, 10(25), 3141–3156.
99.Shao-Feng Lu, Da-Ming Du,* Shi-Wei Zhang, Jiaxi Xu*. Facile synthesis of
C2-symmetric tridentate bis(thiazoline) and bis(oxazoline) ligands and their
application in the enantioselective Henry reaction[J]. Tetrahedron: Asymmetry,
2004, 15 (21), 3433–3441.
100.Bin Fu, Da-Ming Du*, Jianbo Wang. Synthesis of novel C2-symmetric chiral
bis(oxazoline) ligands and their application in the enantioselective addition of
diethylzinc to aldehydes[J]. Tetrahedron: Asymmetry, 2004, 15(1), 119–126.
101.Bin Fu, Da-Ming Du,* Qing Xia. C2-symmetric chiral bis(thiazoline) and
bis(oxazoline) ligands and their application in the catalytic allylic alkylation[J].
Synthesis, 2004, (2), 221–226.
102.Yong-Xin Zhang, Da-Ming Du,* Xiao Chen, Shao-Feng Lü, Wen-Ting Hua.
Enantiospecific synthesis of pyridinylmethyl pyrrolidinemethanols and catalytic
asymmetric borane reduction of prochiral ketones[J]. Tetrahedron: Asymmetry,
2004, 15(1), 177–182.
103.Bin Fu, Da Ming Du,* Qing Xia. Convenient synthesis of bis(oxazoline)
dicarboxylate derivatives[J]. Chinese Chemical Letters, 2004, 15 (4), 383–
385.
104.Xiao Chen, Yong Xin Zhang, Da Ming Du, Wen Ting Hua*. New chiral pyridine
prolinol derivatives and preliminary study on asymmetric catalytic reaction[J].
Chinese Chemical Letters, 2004, 15(2), 167–168.
105.Weifeng Shi, Nan Jiang, Shiwei Zhang, Weiming Wu, Daming Du, Jianbo Wang*.
Unusual reaction of beta-hydroxy alpha-diazo carbonyl compounds with
Cl3CCN/NaH and Rh(II)-catalyzed reaction of beta-trichloroacetylamino
alpha-diazo carbonyl compounds[J]. Organic Letters, 2003, 5(13), 2243–2246.
106.Da-Ming Du,* Bin Fu, Wen-Ting Hua. Novel chiral dibenzo[a,c]cycloheptadiene
bis(oxazoline) and catalytic enantioselective cyclopropanation of styrene[J].
Tetrahedron, 2003, 59(11),1933–1938.
107.Xiao Chen, Da-Ming Du, Wen-Ting Hua*. Synthesis of novel chiral polyamide
macrocycles containing pyridyl side-arm and their molecular recognition
properties[J]. Tetrahedron: Asymmetry, 2003, 14(8), 999–1007.
108.Dong-Cheng Xu, Da-Ming Du,* Nan Ji, Zhan-Yue Wang, Wen-Ting Hua.
Synthesis of novel chiral C2-symmetric bisoxazoline ligands containing
2,5-di(m-substituted)phenyl-1,3,4-oxadiazole[J]. Synthetic Communications, 2003,
33(14), 2563–2574.
109.Zhan-Yue Wang, Da-Ming Du,* Di Wu, Wen-Ting Hua*. Studies on the
synthesis of novel chiral naphthylene bisoxazoline ligands[J]. Synthetic
Communications, 2003, 33(8), 1275–1283.
110.Hui Chen, Da-Ming Du, Wen-Ting Hua, Meiyu He,* Bin Xin. Study of the
fragmentation mechanism of novel functionalized macrocycles by Fourier
transform ion cyclotron resonance mass spectrometry[J]. Journal of Mass
Spectrometry, 2003, 38(8), 839–844.
111.Bin Fu, Da-Ming Du*. Asymmetric Diels-Alder reaction catalyzed by novel chiral
dibenzo[a, c]cycloheptadiene bis(oxazoline) metal complexes[J]. Chinese Journal of
Chemistry, 2003, 21(6), 597–599.
112.杜大明,*  陳曉, 花文廷.  離子液體介質(zhì)中有機合成及催化不對稱反應(yīng)研究新進展[J].  有
機化學, 2003, 23(4), 331–343.
113.杜大明,*  花文廷. 大環(huán)手性磷酰胺對氨基酸衍生物的分子識別研究[J].  高等學�；瘜W
學報, 2003, 24(3), 442–448.
114.Zhan-Yue Wang, Da-Ming Du,* Di Wu, Wen-Ting Hua, Xiang-Lin Jin. Synthesis
and Crystal Structure of N-(1’-Phenyl-2’
-hydroxyethyl)-2,3-naphthylenedicarboximide[J]. Chemical Research in Chinese
Universities, 2003, 19(2), 160–164.
115.Da-Ming Du,* Xiao Chen, Wen-Ting Hua, Xiang-Lin Jin. Reinvestigation the
reaction of salicyclic chloride with salicyclic amide and X-ray crystal structure of a
new macrocyclic polyester[J]. Chinese Journal of Structural Chemistry, 2003, 22(5),
512–516.
116.Hai-Chen Wu, Da-Ming Du, Wen-Ting Hua,* Xiang-Lin Jin. Synthesis and crystal
structure of novel chiral o-hydroxyphenyloxazoline metal complexes[J]. Chinese
Journal of Structural Chemistry, 2003, 22(2), 155–160.
117.Da-Ming Du,* Zhan-Yue Wang, Dong-Cheng Xu, Wen-Ting Hua. Synthesis of
novel chiral bisoxazoline ligands containing 2,5-diaryl-1,3,4-oxadiazole and
enantioselective cyclopropanation of styrene[J]. Synthesis, 2002, (16), 2347–2352.
118.Xiao Chen, Da-Ming Du, Wen-Ting Hua*. A convenient method for synthesis of
trans-4-cyclohexyl-L-proline[J]. Tetrahedron: Asymmetry, 2002, 13(1), 43–46.
119.Xiao Chen, Da Ming Du, Wen Ting Hua*. Synthesis of novel C2-symmetric chiral
polyamide macrocycles containing pyridyl side-arm[J]. Chinese Chemical Letters,
2002, 13(11), 1037–1038.
120.杜大明,*  花文廷. 催化不對稱 Michael 加成反應(yīng)的新進展[J].  有機化學, 2002, 22(3),
164–173.
121.周靈萍,  杜大明, 李宣文,*  王少坤,  周愛秋,  劉建. NaBr/KZSM-5 催化劑在甲苯氧化甲
基化反應(yīng)中的催化性能[J].  北京大學學報(自然科學版), 2002, 38(2), 153–158.
122.Da-Ming Du,* Wen-Ting Hua. One-pot synthesis of macrocyclic chiral
phosphoramidates[J]. Synthetic Communications, 2001, 31(20), 3197–3203.
123.Da-Ming Du,* Wen-Ting Hua, Xiang-Ling Jin. Synthesis and crystal structure of
two new macrocyclic phosphoramidates containing glycine ethyl ester and
2,5-diaryl-1,3,4-oxadiazole[J]. Journal of Molecular Structure, 2001, 561(1-3), 145–
152.
124.Da-Ming Du,* Wen-Ting Hua, Zhe-Ming Wang, Chun-Hua Yan. New chiral
macrocyclic phosphoramidate self-associated by an intermolecular N-HO=P
hydrogen bond[J]. Heteroatom Chemistry, 2001, 12(6), 480–484.
125.Da-Ming Du,* Wen-Ting Hua, Ling-Ping Zhou, Jian-Wu Wang, Xiang-Lin Jin.
Preparation and crystal structure of a 1:1 inclusion compound of
1,4,11,14-tetramethoxy-dibenzo[b,n]tetraphenylene with pyridine[J]. Journal of
Molecular Structure, 2001, 560(1-3), 23–28.
126.杜大明,*  王永梅, 孟繼本,  周秀中.  雙核有機金屬化合物的光化學反應(yīng)[J]. 有機化學,
2001, 21(5), 350–355.
127.Paul R. Carlier,* Da-Ming Du, Yi-Fan Han, Jing Liu, Emanuele Perola, Ian D.
Williams, Yuan-Ping Pang. Dimerization of an inactive fragment of Huperzine A
produces a drug with twice the potency of the natural product[J]. Angewandte
Chemie, International Edition, 2000, 39(10), 1775–1777.
128.Da-Ming Du,* Wen-Ting Hua, Jian-Wu Wang, Xiang-Lin Jin. Syntheses and
molecular self-assembly of chiral phosphoramdates[J]. Chinese Journal of
Chemistry, 2000, 18(5), 764–769.
129.Da-Ming Du,* Lin-Ping Zhou, Jian-Wu Wang, Shao-Kun Wang. Practical
synthesis of new functionalized tetraphenylenes[J]. Chinese Journal of Chemistry,
2000, 18(3), 441–443.
130.Wei Liu, Jianzhuang Jiang,* Daming Du, Ddennis P. Arnold. Synthesis and
spectroscopic properties of homoleptic bis(octakis(octyloxy)phthalocyaninato) rare
earth (III) sandwich complexes[J]. Australian Journal of Chemistry, 2000, 53(2), 131–
135.
131.Tebello Nyokong, Fumio Furuya, Nagao Kobayashi, Daming Du, Wei Liu,
Jianzhuang Jiang*. Comparative spectroscopic and electrochemical properties of
bis(octakis-(dodecylthio)naphthalocyaninato) europium (III) and
bis(tetra-tert-butylnaphthalocyaninato) europium(III) complexes[J]. Inorganic
Chemistry, 2000, 39(1), 128–135.
132.Jianzhuang Jiang,* Wei Liu, Ka-Wo Poon, Daming Du, Dennis P. Arnold, Dennis
K. P. Ng. Synthesis, spectroscopic, and electrochemical properties of rare earth
double-deckers with tetra(tert-butyl)-2,3-naphthalocyaninato ligands[J]. European
Journal of Inorganic Chemistry, 2000, (1), 205–209.
133.Xiao-Ping Yang, Da-Ming Du, Qi Li, Thomas C. W. Mak, Henry N. C. Wong*.
Synthesis, structure and inclusion properties of
1,4,15,18-tetrahedro-1,4,15,18-tetraoxodibenzo-[b,h]tetraphenylene[J]. Chemical
Communications, 1999, (16), 1607–1608.
134.Paul R. Carlier,* Da-Ming Du, Yifan Han, Jing Liu, Yuan-Ping Pan. Potent, easily
synthesized Huperzine A-Tacrine hybrid acetylcholinesterase inhibitors[J].
Bioorganic & Medicinal Chemistry Letters,1999, 9(16), 2335–2338.
135.Jianzhuang Jiang,* Daming Du, M. T. M. Choi, J. L. Xie, Dennis K. P. Ng.
Synthesis and spectroscopic characterization of heteroleptic Europium(III)
double-deckers containing 2,3-naphthalo-cyaninato and tetra(4-pyridyl)-
porphyrinato ligands[J]. Chemical Letters, 1999, (3), 261–262.
136.姜建壯,*  吳基培, 杜大明,  孫思修   三明治型金屬卟啉、酞菁配合物功能材料[J].  大學
化學, 1999, 14(2), 5–8.
137.Da-Ming Du, Feng Xue, Henry N. C. Wong,* Thoms C. W. Mak. Reaction of
2-methylnaphthalene with hexachlorocyclopentadiene and structural
characterization of a new addition-substitution product[J]. Journal of Chemical
Crystallography, 1998, 28(11), 787–790.
138.Da-Ming Du,* Ling-Ping Zhou, Yong-Mei Wang, Ji-Ben Meng. Synthesis and
photoreaction of polymethylenediamine bis(4-methyl-7-coumarinyl)oxyacetic
amides[J]. Chinese Journal of Chemistry, 1998, 16(5), 468–472.
139.Yong-Mei Wang, Zhong Wen, Xiao-Min Chen, Da-Ming Du, T. Matsuura, Ji-Ben
Meng*. Research on photochemical and thermochemical reactions between indole
and quinones in the absence of solevent[J]. J. Heterocyclic Chemistry, 1998, 35(2),
313–316.
140.杜大明*,  王永梅, 孟繼本.  微環(huán)境對長鏈香豆素酯光化學和光物理過程的影響[J].  高等
學�；瘜W學報, 1998, 19(10), 1611–1613.
141.杜大明,*  周靈萍, 孟繼本,  王永梅.  微環(huán)境條件影響的光化學反應(yīng)研究進展[J].合成化
學, 1998, 6(3), 265–271.
142.杜大明,  王永梅, 張慧萍,  孟繼本,*  周秀中.  非共軛雙發(fā)色團體系的光化學 I.  雙香豆
素氧乙酸多次甲基二醇酯的合成及光反應(yīng)研究[J].  化學學報, 1997, 55(2), 189–195.
143.王永梅,  杜大明, 李曉陸,  孟繼本,*  周秀中.  微環(huán)境影響下的乙酰基香豆素與吲哚的固
相光反應(yīng)[J].  有機化學, 1997, 17(5), 433–437.
144.Yong-Mei Wang, Da-Ming Du, Ji-Ben Meng,* Xiu-Zhong Zhou, Lei Wang.
Photochemistry of nonconjugated bischromophoric systems III. Synthesis and
photoreaction of poly(ethylene glycol) biscoumarinyloxyacetates[J]. Chinese
Journal of Chemistry, 1997, 15(2), 169–173.
145.Xiao-Liu Li, Da-Ming Du, Yong-Mei Wang, Ji-Ben Meng*. Solid state reactions
of nitrogenous heterocyclic compounds I. Solid state reactions of
3-methyl-1-phenyl-5-pyrazolone with carbonyl compounds[J]. Science in China
(Series B), 1997, 40(2), 205–214.
146.Xiao-Liu Li, Yong-Mei Wang, Da-Ming Du, Zhong Wen, Guo-Xiang Xiong,
Ji-Ben Meng*. Solid state reactions of nitrogenous heterocyclic compounds II. Solid
state reactions of indole and carbonyl compounds[J]. Science in China (Series B),
1997, 40(3), 270–277.
147.杜大明,  王永梅, 孟繼本,*  周秀中,  王國昌,  梁麗君, 高煥.  非共軛雙發(fā)色團體系的光
化學(II)  長鏈雙香豆素的光環(huán)化反應(yīng)和熒光光譜研究[J]. 高等學校化學學報, 1996, 17(7),
1074–1077.
148.杜大明,  王永梅, 孟繼本*,  周秀中,  張慧萍.  乙�；�香豆素及其衍生物與吲哚的固相光
反應(yīng)研究[J].  高等學校化學學報, 1996, 17(2), 252–254.
149.杜大明,  王永梅, 孟雙明,  梁樹森,  孟繼本,* 周秀中.  1-苯基-3-甲基-5-吡唑啉酮與二
羰基化合物的固相反應(yīng)研究[J].  高等學校化學學報, 1996, 17(1), 81–84.
150.Yong-Mei Wang, Da-Ming Du, Xiao-Min Chen, Ji-Ben Meng,* Hui-Ping Zhang.
Photochemical and thermal reactions of quinones with p-chlorothiophenol in solid
state and in solution[J]. Chemical Research in Chinese Universities, 1996, 12(3), 235
–239.
151.Huan Gao,   Guo-Chang Wang, Li-Jun Liang, Bin-Lin He, Da-Ming Du,
Yong-Mei Wang, Ji-Ben Meng*. Microenvironmental effect on the intramolecular
photochemical interaction of biscoumarinyl compounds containing alkyl chains[J].
Chinese Chemical Letters, 1996, 7(8), 753–755.
152.Da-Ming Du, Yong-Mei Wang, Ji-Ben Meng,* Shuang-Ming Meng, Xiu-Zhong
Zhou, Hong-Gen. Photocycloaddition of (4-methyl-7-coumarinyl)oxyacetic acid
propanediol diester and X-ray crystal structure of product[J]. Chinese Journal of
Structural Chemistry, 1995, 14(4), 272–276.
153.Da-Ming Du, Shuang-Ming Meng, Yong-Mei Wang, Ji-Ben Meng,* Xiu-Zhong
Zhou, Ying Zhu. Solid state synthesis and crystal structure of
3-methyl-1-phenyl-4-phenylbenzoyl-methylene-5-pyrazolone[J]. Chinese Journal
of Structural Chemistry, 1995, 14(4), 277–280.
154.Da-Ming Du, Shuang-Ming Meng, Yong-Mei Wang, Ji-Ben Meng,* Xiu-Zhong
Zhou. Solid state reaction of aromatic ketones with heteroaromatics[J]. Chinese
Journal of Chemistry, 1995, 13(6), 520–524.
155.Da-Ming Du, Yong-Mei Wang, Guo-Xiang Xiong, Wen-Guang Wang, Ji-Ben
Meng*. Solid state photochemistry of nitrobenzaldehydes[J]. Chemical Research in
Chinese Universities 1995, 11(2), 111–116.
156.孟繼本,*  王文廣, 杜大明,  熊國祥,  王永梅. 含氮雜環(huán)化合物的固相光化學[J].  化學學報, 1995, 53(6), 595–602.
157.孟繼本,*  杜大明, 王文廣,  王永梅.  吲哚類新主體化合物的固相光化學合成及包結(jié)性能研究[J].  高等學�；瘜W學報, 1994, 15(4), 528–531.
158.Ji-Ben Meng; Da-Ming Du, Guo-Xiang Xiong, Wen-Guang Wang, Yong-Mei Wang, H. Koshima, T. Matsuura*. A dual pathway in the solid-state photoreaction of nitrobenzaldehydes with Indole[J]. Journal of Heterocyclic Chemistry, 1994, 31(1),121–124.
159.Ji-Ben Meng,* Da-Ming Du, Yong-Mei Wang, Hong-Gen Wang, Ru-Ji Wang.
The synthesis and X-ray crystal structure studies of (di-3-indolyl)methylferrocene[J].
Chinese Journal of Structural Chemistry, 1993, 12(2), 85–88.
160.Ji-Ben Meng, Wen-Guang Wang, Guo-Xiang Xiong, Yong-Mei Wang, De-Chao
Fu, Da-Ming Du, Ru-Ji Wang, Hong-Gen Wang, H. Koshima, T. Matsuura*. A
multistep photoreaction of aromatic aldehydes with heteroaromatics in the solid
state[J]. Journal Photochemistry and Photobiology A: Chemistry, 1993, 74(1), 43–49.
161.Ji-Ben Meng,* Da-Ming Du, Yong-Mei Wang, Hong-Gen Wang, Ru-Ji Wang.
Solid state photochemical synthesis of a novel host compound methyl
4-(di-3-indolyl)-methylbenzoate and X-ray crystal structure of its 1:1 inclusion
complex with acetone[J]. Chinese Journal of Structural Chemistry, 1992, 11(5), 358–
361.
162.Ji-Ben Meng,* Da-Ming Du, Guo-Xiang Xiong, Wen-Guang Wang, Yong-Mei
Wang. The solid state controlled photochemical reaction of nitrobenzaldehydes
with indole[J]. Chinese Chemical Letters, 1992, 3(11), 865.
163.Ji-Ben Meng,* Da-Ming Du, Yong-Mei Wang, Ru-Ji Wang, Hong-Gen Wang.
The solid state controlled condensation reaction of ferrocenealdehyde and
indole[J]. Chinese Chemical Letters, 1992, 3(4), 247.
 
科研項目

1.方酰胺催化不對稱加成與串聯(lián)反應(yīng)合成雜環(huán)化合物研究. (國家自然科學基金面上項目，項目負責人)
2.模塊組裝合成多齒手性配體及在不對稱催化反應(yīng)中的應(yīng)用研究. (國家自然科學基金面上項目，項目負責人)
3.手性方酰胺催化不對稱串聯(lián)反應(yīng)合成含氮雜環(huán)化合物研究. (元素有機化學國家重點實驗室基金項目，項目負責人)
4.新型手性配體及催化劑設(shè)計合成與高效不對稱催化研究.?(北京理工大學科技創(chuàng)新計劃重大項目培育專項計劃,  項目負責人)
5.三齒手性配體的合成與不對稱催化反應(yīng)研究. (國家自然科學基金面上項目，項目負責人)
6.新型 C3 對稱性手性配體的合成及其在不對稱催化反應(yīng)中的應(yīng)用. (國家自然科學基金面上項目，項目負責人)
7.教育部新世紀優(yōu)秀人才支持計劃. (國家教育部人才項目，項目負責人)
8.有機合成化學與方法學. (國家自然科學基金會創(chuàng)新群體項目，項目參加人)
9.新雜環(huán)手性配體的合成與不對稱催化反應(yīng)研究. (國家自然科學基金面上項目，項目負責人)
10.新手性雙噁唑啉催化劑的設(shè)計合成與不對稱催化反應(yīng)研究. (國家自然科學基金面上項目，項目負責人)
11.手性磷酰胺主體化合物的合成、分子識別及應(yīng)用基礎(chǔ)研究. (國家自然科學基金面上項目，項目負責人)
12.BG-1 原料藥合成實驗工藝的開發(fā)研究. (橫向項目，項目共同負責人)
13.新模板劑的合成. (橫向項目，項目負責人)
14.新型苯并環(huán)辛四烯超分子體系的設(shè)計合成和結(jié)構(gòu)鑒定. (留學歸國人員啟動基金項目，項目負責人)
15.手性磷酰胺主體的合成與分子識別. (中國博士后科學基金項目，項目負責人)
 
授權(quán)專利

1.Dimeric Compounds (Dimeric 5-amino-5,6,7,8-tetrahydroquinolinones and their
pharmaceutical use). United Kingdom Patent No: GB 2360518 A.
2.Dimeric Compounds (Dimeric 5-amino-5,6,7,8-tetrahydroquinolinones and their
pharmaceutical use). United States Patent No: US 6472408 B1.
3.一種簡便合成康普立停 A-4 前藥的方法. 中國專利號: ZL 02120895.6
4.手性二苯并[a,c]環(huán)庚二烯雙噁唑啉配體化合物及其制備與應(yīng)用.  中國專利號:ZL03101899.8
5.一種有機磷酸催化劑及其制備方法和應(yīng)用.  中國專利號: ZL 200710175800.7
6.一種雙咪唑啉二苯胺類化合物及其制備方法.  中國專利號: ZL 200910243257.9.
7.一種噁唑啉西佛堿配體金屬絡(luò)合物催化劑及其應(yīng)用.  中國專利號: ZL 201010034468.4
8.一種三苯基氧磷連接雙噁唑啉配體化合物及其制備方法.  中國專利號: ZL201110255694.X
9.取代�；撬嵫苌�物及其制備方法.  中國專利號: ZL 200510011724.7
10.亞膦酰肽及其制備方法.  中國專利號: ZL 200710086598.0
11.�；撬峒捌溲苌�物制備.  中國專利號: ZL 200710064146.2
12.一種取代�；撬岬闹苽浞椒�.  中國專利號: ZL 200710175915.6
13.光酸聚合物摻雜的螺噁嗪或螺吡喃可逆光致變色薄膜及其制備方法和用途.  中國專利號:
ZL 200710099452.X